Earnings review- Gilead sciences(GILD) Q2 2026

Muffett Investments
Earnings Watch · Stock Analysis Division
Earnings Review
5 August 2026
◆ Healthcare · Biotechnology & Oncology
Gilead Sciences, Inc.
GILD NASDAQ · Mkt Cap: $166.7B · Q2 FY2026 Results
Report Period
Q2 FY2026
Reported: 2026-08-04
Headline Beat Expectations ✓ Lenacapavir & HIV Surge (+12% YoY)
Key Metrics at a Glance
Total Revenue
$7.80B
+10.0% YoY
HIV Sales
$5.70B
+12.0% YoY
Biktarvy Sales
$3.80B
+7.0% YoY
PrEP Franchise
>$1.00B
+101% YoY Surge
🛡
Base Business
$7.60B
+10.0% YoY
Financial Metrics — Detailed Breakdown
Metric Q2 FY2026 Q2 FY2025 YoY Change Consensus Est. vs. Estimate
Total Revenue $7.80B $7.09B +10.0% $7.45B BEAT
Base Business Revenue $7.60B $6.91B +10.0% $7.30B BEAT
Biktarvy Sales (HIV) $3.80B $3.55B +7.0% $3.72B BEAT
Yeztugo (Lenacapavir PrEP) $232M $165M +40.6% QoQ $200M BEAT
Oncology & Cell Therapy $885M $815M +8.6% $860M BEAT
Operating Cash Flow $2.45B $2.15B +13.95% $2.20B BEAT
Non-GAAP Operating Margin 44.2% 42.5% +170bps 43.0% BEAT
⚡ Management Commentary & Guidance Signals
  • FY2026 HIV Growth Guidance Raised "Raised full-year 2026 HIV sales growth guidance to 9%–10% driven by accelerating adoption of long-acting lenacapavir regimens."
  • Upcoming BIC/LEN FDA PDUFA Approval "PDUFA action target date set for August 27, 2026 for the once-daily fixed-dose combination of bictegravir and lenacapavir."
  • PrEP Franchise Milestone Exceeded "HIV PrEP product sales exceeded $1.0 Billion in a single quarter for the first time (+101% YoY growth), backed by Yeztugo."
📈 Price Reaction & Technical Structure
Pre-Earnings Close
$126.50
2026-08-03
Post-Earnings Price
$135.27
Next trading session
1-Day Move
+6.93%
vs. S&P 500
52-Week Range
$74.50 – $138.00
All-Time High Test
−10%0%+10%
Stock surged +6.93% post-earnings, breaking past $135 resistance into a multi-year Stage 2 uptrend extension.
Our Verdict
5 / 5 — Beat Expectations
Constructive / Target $155.00

Gilead delivered an outstanding Q2 2026 earnings beat, highlighted by 10% YoY total revenue expansion ($7.80B) and a landmark 12% surge in HIV franchise sales ($5.70B). The unprecedented commercial momentum behind twice-yearly Lenacapavir (Yeztugo) in HIV prevention validates Gilead's unassailable competitive moat. We maintain a High Conviction Buy with a price target of $155.00.

  • Top-Line Acceleration: Revenue reached $7.80B (+10% YoY), easily surpassing Wall Street estimates ($7.45B).
  • Lenacapavir Disruption: PrEP business eclipsed $1.0B in a single quarter (+101% YoY), solidifying long-acting dominance.
  • Guidance Hike: Management raised full-year HIV sales growth targets to 9%–10%.
  • Imminent Catalyst: FDA PDUFA date for once-daily BIC/LEN combination arrives August 27, 2026.
  • Technical Momentum: Stock expanded +6.93% post-earnings to $135.27, targeting $155.00 (+14.6% upside).

This analysis is produced by Muffett Investments for informational purposes only and does not constitute financial advice or a recommendation to buy or sell any security. Data sourced from Yahoo Finance and SEC EDGAR. Past performance is not indicative of future results.

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